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Bladder Tissue Pharmacokinetics of Intravesical Mitomycin C and Suramin in Dogs

Suramin, at non-cytotoxic doses, reverses chemoresistance and enhances the activity of mitomycin C (MMC) in mice bearing human bladder xenograft tumors. The present study evaluated the pharmacokinetics of the intravesical suramin and MMC, alone or in combination, in dogs. Animals received either hig...

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Bibliografiska uppgifter
Huvudupphovsmän: Hu, Leijun, Wientjes, M. Guillaume, Li, Jing, Au, Jessie L.-S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976994/
https://ncbi.nlm.nih.gov/pubmed/20625863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9219-8
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