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Acute Methadone Treatment Reduces Myocardial Infarct Size via the δ-Opioid Receptor in Rats During Reperfusion

BACKGROUND: Methadone is an opioid agonist often given to manage acute and chronic pain. We sought to determine whether methadone compared with morphine dose dependently reduces myocardial infarct size (IS) and whether the mechanism is δ-opioid receptor mediated. Furthermore, we examined whether myo...

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Detalhes bibliográficos
Main Authors: Gross, Eric R., Hsu, Anna K., Gross, Garrett J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877584/
https://ncbi.nlm.nih.gov/pubmed/19843777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3181b92201
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