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Acute Methadone Treatment Reduces Myocardial Infarct Size via the δ-Opioid Receptor in Rats During Reperfusion

BACKGROUND: Methadone is an opioid agonist often given to manage acute and chronic pain. We sought to determine whether methadone compared with morphine dose dependently reduces myocardial infarct size (IS) and whether the mechanism is δ-opioid receptor mediated. Furthermore, we examined whether myo...

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Détails bibliographiques
Auteurs principaux: Gross, Eric R., Hsu, Anna K., Gross, Garrett J.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877584/
https://ncbi.nlm.nih.gov/pubmed/19843777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3181b92201
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