Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats

AIMS: Thrombopoietin (Tpo) is known for its ability to stimulate platelet production. However, it is currently unknown whether Tpo plays a physiological function in the heart. METHODS AND RESULTS: We assessed the potential protective role of Tpo in vitro and in vivo in two rat models of myocardial i...

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Autori principali: Baker, John E., Su, Jidong, Hsu, Anna, Shi, Yang, Zhao, Ming, Strande, Jennifer L., Fu, Xiangping, Xu, Hao, Eis, Annie, Komorowski, Richard, Jensen, Eric S., Tweddell, James S., Rafiee, Parvaneh, Gross, Garrett J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958050/
https://ncbi.nlm.nih.gov/pubmed/18006466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvm026
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