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A Stabilized Demethoxyviridin Derivative Inhibits PI3 kinase
The viridins like demethoxyviridin (Dmv) and wortmannin (Wm) are nanomolar inhibitors of the PI3 kinases, a family of enzymes that play key roles in a host of regulatory processes. Central to the use of these compounds to investigate the role of PI3 kinase in biological systems, or as scaffolds for...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877487/ https://ncbi.nlm.nih.gov/pubmed/19523825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.05.105 |
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