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A Wortmannin-Cetuximab As A Double Drug
Double drugs are obtained when two pharmacologically active entities are covalently joined to improve potency. We conjugated the viridin Wm with a self-activating linkage to cetuximab and demonstrated the retention of immunoreactivity by the conjugate. Though cetuximab lacked a growth inhibitory act...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386608/ https://ncbi.nlm.nih.gov/pubmed/19883074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900176a |
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