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Orm family proteins mediate sphingolipid homeostasis
Despite the essential roles of sphingolipids as both structural components of membranes and critical signalling molecules, we have a limited understanding of how cells sense and regulate their levels. Here we reveal the function in sphingolipid metabolism of the ORM/ORMDL genes, a conserved gene fam...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877384/ https://ncbi.nlm.nih.gov/pubmed/20182505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08787 |
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