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β-Lapachone suppresses radiation-induced activation of nuclear factor-κB
Anticancer effects of β-lapachone (β-lap) are due to generation of ROS and metabolic catastrophes as a result of NAD(P)H:quinone oxidoreductase (NQO1)-mediated futile cycling between the oxidized and reduced forms of β-lap. It has been shown that NQO1 is also essential for the TNF-induced activation...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Korean Society for Biochemistry and Molecular Biology
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877251/ https://ncbi.nlm.nih.gov/pubmed/20200474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.5.034 |
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