Chromosome copy number changes carry prognostic information independent of KIT/PDGFRA point mutations in gastrointestinal stromal tumors

BACKGROUND: Oncogenic point mutations in KIT or PDGFRA are recognized as the primary events responsible for the pathogenesis of most gastrointestinal stromal tumors (GIST), but additional genomic alterations are frequent and presumably required for tumor progression. The relative contribution of suc...

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Bibliographische Detailangaben
Hauptverfasser: Silva, Mara, Veiga, Isabel, Ribeiro, Franclim R, Vieira, Joana, Pinto, Carla, Pinheiro, Manuela, Mesquita, Bárbara, Santos, Catarina, Soares, Marta, Dinis, José, Santos, Lúcio, Lopes, Paula, Afonso, Mariana, Lopes, Carlos, Teixeira, Manuel R
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876987/
https://ncbi.nlm.nih.gov/pubmed/20470368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-8-26
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