Functional Characterization of TtnD and TtnF Unveiling New Insights into Tautomycetin Biosynthesis

The biosynthetic gene cluster for tautomycetin (TTN), a highly potent and selective protein phosphatase (PP) inhibitor isolated from Streptomyces griseochromogenes, has recently been cloned and sequenced. To better understand the transformations responsible for converting the post-polyketide synthas...

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Detalhes bibliográficos
Main Authors: Luo, Yinggang, Li, Wenli, Ju, Jianhua, Yuan, Qiuping, Peters, Noel R., Hoffmann, F. Michael, Huang, Shengxiong, Bugni, Tim S., Rajski, Scott, Osada, Hiroyuki, Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876980/
https://ncbi.nlm.nih.gov/pubmed/20426415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9082446
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