Nuclear deadenylation/polyadenylation factors regulate 3′ processing in response to DNA damage

We previously showed that mRNA 3′ end cleavage reaction in cell extracts is strongly but transiently inhibited under DNA-damaging conditions. The cleavage stimulation factor-50 (CstF-50) has a role in this response, providing a link between transcription-coupled RNA processing and DNA repair. In thi...

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Detalhes bibliográficos
Main Authors: Cevher, Murat A, Zhang, Xiaokan, Fernandez, Sully, Kim, Sergey, Baquero, Jorge, Nilsson, Per, Lee, Sean, Virtanen, Anders, Kleiman, Frida E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876964/
https://ncbi.nlm.nih.gov/pubmed/20379136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.59
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