Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA

The DNA damage response involves coordinated control of gene expression and DNA repair. Using deep sequencing, we found widespread changes of alternative cleavage and polyadenylation site usage on ultraviolet-treatment in mammalian cells. Alternative cleavage and polyadenylation regulation in the 3ʹ...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Devany, Emral, Park, Ji Yeon, Murphy, Michael R, Zakusilo, George, Baquero, Jorge, Zhang, Xiaokan, Hoque, Mainul, Tian, Bin, Kleiman, Frida E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906801/
https://ncbi.nlm.nih.gov/pubmed/27462460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.13
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