Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress

Recent studies have shown a critical function for the ubiquitin-proteasome system (UPS) in regulating the signalling network for DNA damage responses and DNA repair. To search for new UPS targets in the DNA damage signalling pathway, we have carried out a non-biased assay to identify fast-turnover p...

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Main Authors: Zhang, Liyong, Park, Chi-Hoon, Wu, Jing, Kim, Hyun, Liu, Weijun, Fujita, Takeo, Balasubramani, Manimalha, Schreiber, Emanuel M, Wang, Xiao-Fan, Wan, Yong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876963/
https://ncbi.nlm.nih.gov/pubmed/20424596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.55
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