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Regulation of natural killer T-cell development by deubiquitinase CYLD
Natural killer T (NKT) cells modulate immune responses against pathogens and tumours, as well as immunological tolerance. We show here that CYLD, a tumour suppressor with deubiquitinase function, has a pivotal and cell-intrinsic function in NKT cell development. Unlike other known NKT regulators, CY...
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Hauptverfasser: | , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Nature Publishing Group
2010
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876956/ https://ncbi.nlm.nih.gov/pubmed/20224552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.31 |
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