Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawless

To achieve accurate gene regulation, some homeodomain proteins bind cooperatively to DNA to increase those site specificities. We report a ternary complex structure containing two homeodomain proteins, aristaless (Al) and clawless (Cll), bound to DNA. Our results show that the extended conserved seq...

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Hauptverfasser: Miyazono, Ken-ichi, Zhi, Yuehua, Takamura, Yuriko, Nagata, Koji, Saigo, Kaoru, Kojima, Tetsuya, Tanokura, Masaru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876955/
https://ncbi.nlm.nih.gov/pubmed/20389279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.53
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