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Distortion of double-stranded DNA structure by the binding of the restriction DNA glycosylase R.PabI

R.PabI is a restriction DNA glycosylase that recognizes the sequence 5′-GTAC-3′ and hydrolyses the N-glycosidic bond of adenine in the recognition sequence. R.PabI drastically bends and unwinds the recognition sequence of double-stranded DNA (dsDNA) and flips the adenine and guanine bases in the rec...

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Pubblicato in:Nucleic Acids Res
Autori principali: Miyazono, Ken-ichi, Wang, Delong, Ito, Tomoko, Tanokura, Masaru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229829/
https://ncbi.nlm.nih.gov/pubmed/32232412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa184
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