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Parkinson disease protein DJ-1 converts from a zymogen to a protease by carboxyl-terminal cleavage
Mutations in DJ-1 cause recessively transmitted early-onset Parkinson disease (PD), and oxidative damage to DJ-1 has been associated with the pathogenesis of late-onset sporadic PD. The precise biochemical function of DJ-1 remains elusive. Here, we report that DJ-1 is synthesized as a latent proteas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876885/ https://ncbi.nlm.nih.gov/pubmed/20304780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq113 |
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