An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist

BACKGROUND: Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or autoreactive T cells. We report a disorder caused by mutations of IL1RN, which encodes the interleukin-1–receptor antagonist, with prominent involvement of skin and bone. METHODS:...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Aksentijevich, Ivona, Masters, Seth L., Ferguson, Polly J., Dancey, Paul, Frenkel, Joost, van Royen-Kerkhoff, Annet, Laxer, Ron, Tedgård, Ulf, Cowen, Edward W., Pham, Tuyet-Hang, Booty, Matthew, Estes, Jacob D., Sandler, Netanya G., Plass, Nicole, Stone, Deborah L., Turner, Maria L., Hill, Suvimol, Butman, John A., Schneider, Rayfel, Babyn, Paul, El-Shanti, Hatem I., Pope, Elena, Barron, Karyl, Bing, Xinyu, Laurence, Arian, Lee, Chyi-Chia R., Chapelle, Dawn, Clarke, Gillian I., Ohson, Kamal, Nicholson, Marc, Gadina, Massimo, Yang, Barbara, Korman, Benjamin D., Gregersen, Peter K., van Hagen, P. Martin, Hak, A. Elisabeth, Huizing, Marjan, Rahman, Proton, Douek, Daniel C., Remmers, Elaine F., Kastner, Daniel L., Goldbach-Mansky, Raphaela
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876877/
https://ncbi.nlm.nih.gov/pubmed/19494218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0807865
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk