Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

Mitochondria are highly mobile and dynamic organelles that continually fuse and divide. These processes allow mitochondria to exchange contents, including mitochondrial DNA (mtDNA). Here we examine the functions of mitochondrial fusion in differentiated skeletal muscle through conditional deletion o...

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Autori principali: Chen, Hsiuchen, Vermulst, Marc, Wang, Yun E., Chomyn, Anne, Prolla, Tomas A., McCaffery, J. Michael, Chan, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876819/
https://ncbi.nlm.nih.gov/pubmed/20403324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.02.026
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