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Recognition of the Ring-Opened State of Proliferating Cell Nuclear Antigen by Replication Factor C Promotes Eukaryotic Clamp-Loading

[Image: see text] Proliferating cell nuclear antigen (PCNA, sliding clamp) is a toroidal-shaped protein that encircles DNA and plays a pivotal role in DNA replication, modification and repair. To perform its vital functions, the clamp has to be opened and resealed at primer−template junctions by a c...

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Bibliographische Detailangaben
Hauptverfasser: Tainer, John A., McCammon, J. Andrew, Ivanov, Ivaylo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876781/
https://ncbi.nlm.nih.gov/pubmed/20455582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100365x
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