Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: A randomized, double–blind, placebo-controlled, crossover pilot study

INTRODUCTION: Three common haplotypes in the gene encoding catechol-O-methyltransferase (COMT) have been associated with pain modulation and the risk of developing chronic musculoskeletal pain, namely temporomandibular disorder (TMD). Haplotypes coding for higher enzymatic activity were correlated w...

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Detalhes bibliográficos
Main Authors: Tchivileva, Inna E., Lim, Pei Feng, Smith, Shad B., Slade, Gary D., Diatchenko, Luda, McLean, Samuel A., Maixner, William
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876724/
https://ncbi.nlm.nih.gov/pubmed/20216107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328337f9ab
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