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CXCL4 Downregulates the Atheroprotective Hemoglobin Receptor CD163 in Human Macrophages
RATIONALE: CXCL4 is a platelet-derived chemokine that promotes macrophage differentiation from monocytes. Deletion of the PF4 gene that encodes CXCL4 reduces atherosclerotic lesions in ApoE(−/−) mice. OBJECTIVE: We sought to study effects of CXCL4 on macrophage differentiation with possible relevanc...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876722/ https://ncbi.nlm.nih.gov/pubmed/19910578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.199505 |
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