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A Five-Year Longitudinal Analysis of Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus Reveals a Slow but Progressive Decline in CD4(+) T-Cell Count Whose Magnitude Is Not Predicted by Viral Load or Immune Activation

Natural simian immunodeficiency virus (SIV) infection in sooty mangabeys (SMs) typically does not result in AIDS, despite high-level viremia and significant depletion of mucosal CD4(+) T cells. Here, we report the results of the first longitudinal study of a large cohort of SMs naturally infected wi...

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Detalhes bibliográficos
Main Authors: Taaffe, Jessica, Chahroudi, Ann, Engram, Jessica, Sumpter, Beth, Meeker, Tracy, Ratcliffe, Sarah, Paiardini, Mirko, Else, James, Silvestri, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876601/
https://ncbi.nlm.nih.gov/pubmed/20335252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00039-10
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