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A Five-Year Longitudinal Analysis of Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus Reveals a Slow but Progressive Decline in CD4(+) T-Cell Count Whose Magnitude Is Not Predicted by Viral Load or Immune Activation

Natural simian immunodeficiency virus (SIV) infection in sooty mangabeys (SMs) typically does not result in AIDS, despite high-level viremia and significant depletion of mucosal CD4(+) T cells. Here, we report the results of the first longitudinal study of a large cohort of SMs naturally infected wi...

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Bibliografische gegevens
Hoofdauteurs: Taaffe, Jessica, Chahroudi, Ann, Engram, Jessica, Sumpter, Beth, Meeker, Tracy, Ratcliffe, Sarah, Paiardini, Mirko, Else, James, Silvestri, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876601/
https://ncbi.nlm.nih.gov/pubmed/20335252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00039-10
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