In Vitro and In Vivo Characterization of the Pseudomonas aeruginosa Cyclic AMP (cAMP) Phosphodiesterase CpdA, Required for cAMP Homeostasis and Virulence Factor Regulation

Cyclic AMP (cAMP) is an important second messenger signaling molecule that controls a wide variety of eukaryotic and prokaryotic responses to extracellular cues. For cAMP-dependent signaling pathways to be effective, the intracellular cAMP concentration is tightly controlled at the level of synthesi...

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Main Authors: Fuchs, Erin L., Brutinel, Evan D., Klem, Erich R., Fehr, Anthony R., Yahr, Timothy L., Wolfgang, Matthew C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876501/
https://ncbi.nlm.nih.gov/pubmed/20348254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00168-10
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