Učitavanje...

The M230L Nonnucleoside Reverse Transcriptase Inhibitor Resistance Mutation in HIV-1 Reverse Transcriptase Impairs Enzymatic Function and Viral Replicative Capacity

The M230L mutation in HIV-1 reverse transcriptase (RT) is associated with resistance to first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs). The present study was designed to determine the effects of M230L on enzyme function, viral replication capacity (RC), and the extent to wh...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Xu, Hong-Tao, Quan, Yudong, Schader, Susan M., Oliveira, Maureen, Bar-Magen, Tamara, Wainberg, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876396/
https://ncbi.nlm.nih.gov/pubmed/20308384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01795-09
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!