Human Immunodeficiency Virus Type 1 Recombinant Reverse Transcriptase Enzymes Containing the G190A and Y181C Resistance Mutations Remain Sensitive to Etravirine

Etravirine (ETR) is a second-generation nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) active against common human immunodeficiency virus type 1 (HIV-1) drug-resistant strains. This study was designed to determine the extent to which each of the Y181C or G190A mutations in RT might confe...

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Main Authors: Xu, Hongtao, Quan, Yudong, Brenner, Bluma G., Bar-Magen, Tamara, Oliveira, Maureen, Schader, Susan M., Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772356/
https://ncbi.nlm.nih.gov/pubmed/19704127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00800-09
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