Population Pharmacokinetics and Pharmacodynamic Considerations of Amodiaquine and Desethylamodiaquine in Kenyan Adults with Uncomplicated Malaria Receiving Artesunate-Amodiaquine Combination Therapy

Amodiaquine (AQ) is an antimalarial drug that was frequently combined with artesunate (AS) for the treatment of uncomplicated malaria due to Plasmodium falciparum and is now available as a fixed-dose combination. Despite its widespread use, the simultaneous pharmacokinetics in patients of AQ and its...

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Detalhes bibliográficos
Main Authors: Jullien, Vincent, Ogutu, Bernhards, Juma, Elizabeth, Carn, Gwenaelle, Obonyo, Charles, Kiechel, Jean-René
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876388/
https://ncbi.nlm.nih.gov/pubmed/20368402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01496-09
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