Pharmacokinetics of Sulfobutylether-Beta-Cyclodextrin and Voriconazole in Patients with End-Stage Renal Failure during Treatment with Two Hemodialysis Systems and Hemodiafiltration

Sulfobutylether-beta-cyclodextrin (SBECD), a large cyclic oligosaccharide that is used to solubilize voriconazole (VRC) for intravenous administration, is eliminated mainly by renal excretion. The pharmacokinetics of SBECD and voriconazole in patients undergoing extracorporeal renal replacement ther...

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Hlavní autoři: Hafner, Verena, Czock, David, Burhenne, Jürgen, Riedel, Klaus-Dieter, Bommer, Jürgen, Mikus, Gerd, Machleidt, Christoph, Weinreich, Thomas, Haefeli, Walter E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876385/
https://ncbi.nlm.nih.gov/pubmed/20368400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01540-09
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