Pharmacokinetics of Sulfobutylether-Beta-Cyclodextrin and Voriconazole in Patients with End-Stage Renal Failure during Treatment with Two Hemodialysis Systems and Hemodiafiltration

Sulfobutylether-beta-cyclodextrin (SBECD), a large cyclic oligosaccharide that is used to solubilize voriconazole (VRC) for intravenous administration, is eliminated mainly by renal excretion. The pharmacokinetics of SBECD and voriconazole in patients undergoing extracorporeal renal replacement ther...

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Main Authors: Hafner, Verena, Czock, David, Burhenne, Jürgen, Riedel, Klaus-Dieter, Bommer, Jürgen, Mikus, Gerd, Machleidt, Christoph, Weinreich, Thomas, Haefeli, Walter E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876385/
https://ncbi.nlm.nih.gov/pubmed/20368400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01540-09
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