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In Vivo Comparison of the Pharmacodynamic Targets for Echinocandin Drugs against Candida Species

Previous pharmacodynamic studies using in vivo candidiasis models have demonstrated that the 24-h area under the concentration-time curve (AUC)/MIC is a good descriptor of the echinocandin exposure-response relationship. Further studies investigating the 24-h AUC/MIC target for a stasis endpoint ide...

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Bibliographic Details
Main Authors: Andes, D., Diekema, D. J., Pfaller, M. A., Bohrmuller, J., Marchillo, K., Lepak, A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876357/
https://ncbi.nlm.nih.gov/pubmed/20385855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01584-09
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