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Decoupling mutations in the D-channel of the aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides suggest that a continuous hydrogen-bonded chain of waters is essential for proton pumping

The aa(3)-type cytochrome c oxidase from Rhodobacter sphaeroides utilizes two proton-input channels to provide all the protons for chemistry (water formation) and proton pumping. The D-channel is responsible for the uptake of all pumped protons, 4 protons per O(2). Several substitutions for either N...

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מידע ביבליוגרפי
Main Authors: Zhu, Jiapeng, Han, Huazhi, Pawate, Ashtamurthy, Gennis, Robert B.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876219/
https://ncbi.nlm.nih.gov/pubmed/20441187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100344x
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