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Replacing Asn207 by Aspartate at the Neck of the D Channel in the aa(3)-type Cytochrome c Oxidase from Rhodobacter sphaeroides Results in Decoupling the Proton Pump

Cytochrome oxidase catalyzes the reduction of O(2) to water and conserves the considerable free energy available from this reaction in the form of a proton motive force. For each electron, one proton is electrogenically pumped across the membrane. Of particular interest is the mechanism by which the...

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Detalhes bibliográficos
Main Authors: Han, Dan, Namslauer, Andreas, Pawate, Ashtamurthy, Morgan, Joel E., Nagy, Stanislav, Vakkasoglu, Ahmet S., Brzezinski, Peter, Gennis, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535581/
https://ncbi.nlm.nih.gov/pubmed/17115701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061465q
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