A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling

BACKGROUND: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a standard set of probes measuring the methylation status of CpG sites across the whole genome is that many sites may not s...

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Detalhes bibliográficos
Main Authors: Meng, Hailong, Joyce, Andrew R, Adkins, Daniel E, Basu, Priyadarshi, Jia, Yankai, Li, Guoya, Sengupta, Tapas K, Zedler, Barbara K, Murrelle, E Lenn, van den Oord, Edwin JCG
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Methodology article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876131/
https://ncbi.nlm.nih.gov/pubmed/20441598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-227
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