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Non-homologous isofunctional enzymes: A systematic analysis of alternative solutions in enzyme evolution

BACKGROUND: Evolutionarily unrelated proteins that catalyze the same biochemical reactions are often referred to as analogous - as opposed to homologous - enzymes. The existence of numerous alternative, non-homologous enzyme isoforms presents an interesting evolutionary problem; it also complicates...

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Main Authors: Omelchenko, Marina V, Galperin, Michael Y, Wolf, Yuri I, Koonin, Eugene V
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876114/
https://ncbi.nlm.nih.gov/pubmed/20433725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-31
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