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Possible important pair of acidic residues in vesicular acetylcholine transporter

Invariant E309 is in contact with critical and invariant D398 in a three-dimensional homology model of vesicular acetylcholine transporter (VAChT, TC# 2.A.1.2.13). In the work reported here, E309 and D398 in human VAChT were mutated singly and together to test their functions, assign pK values to th...

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Detalhes bibliográficos
Main Authors: Khare, Parul, Ojeda, Ana M., Chandrasekaran, Ananda, Parsons, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875949/
https://ncbi.nlm.nih.gov/pubmed/20225888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901953j
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