High Expression of Pitx-2 in the ICAT-deficient Metanephros Leads to Developmental Arrest

ICAT (Inhibitor of β-catenin and T cell factor) inhibits the interaction between β-catenin and TCF/LEF transcription factor and serves as a negative regulator of Wnt signaling. In a subset of ICAT knockout mice, significant delay in the ureteric bud branching and renal agenesis are observed. In orde...

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Bibliografiska uppgifter
Huvudupphovsmän: Hasegawa, Yoshimi, Iizuka-Kogo, Akiko, Akiyama, Tetsu, Senda, Takao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Japan Society of Histochemistry and Cytochemistry 2010
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875859/
https://ncbi.nlm.nih.gov/pubmed/20514292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.09028
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