Requirement of DLG1 for Cardiovascular Development and Tissue Elongation during Cochlear, Enteric, and Skeletal Development: Possible Role in Convergent Extension

The Dlg1 gene encodes a member of the MAGUK protein family involved in the polarization of epithelial cells. Null mutant mice for the Dlg1 gene (Dlg1(-/-) mice) exhibit respiratory failure and cyanosis, and die soon after birth. However, the cause of this neonatal lethality has not been determined....

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Veröffentlicht in:PLoS One
Hauptverfasser: Iizuka-Kogo, Akiko, Senda, Takao, Akiyama, Tetsu, Shimomura, Atsushi, Nomura, Ryuji, Hasegawa, Yoshimi, Yamamura, Ken-ichi, Kogo, Hiroshi, Sawai, Nobuhiko, Matsuzaki, Toshiyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4393223/
https://ncbi.nlm.nih.gov/pubmed/25860837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123965
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