Calmodulin-Dependent Kinase II Mediates Vascular Smooth Muscle Cell Proliferation and Is Potentiated by Extracellular Signal Regulated Kinase

Vascular smooth muscle cell (VSMC) proliferation contributes to vascular remodeling in atherosclerosis and hypertension. Calcium-dependent signaling through calcium/calmodulin-dependent kinase II (CaMKII) and ERK1/2 activation plays an important role in the regulation of VSMC proliferation by agents...

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Main Authors: Cipolletta, E., Monaco, S., Maione, A. S., Vitiello, L., Campiglia, P., Pastore, L., Franchini, C., Novellino, E., Limongelli, V., Bayer, K. U., Means, A. R., Rossi, G., Trimarco, B., Iaccarino, G., Illario, M.
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875822/
https://ncbi.nlm.nih.gov/pubmed/20392834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1248
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