Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells

Microbial products, including lipopolysaccharide (LPS), an agonist of Toll-like receptor 4 (TLR4), regulate the lifespan of dendritic cells (DCs) by largely undefined mechanisms. Here, we identify a role for calcium-calmodulin–dependent kinase IV (CaMKIV) in this survival program. The pharmacologic...

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Bibliografski detalji
Glavni autori: Illario, Maddalena, Giardino-Torchia, Maria L., Sankar, Uma, Ribar, Thomas J., Galgani, Mario, Vitiello, Laura, Masci, Anna Maria, Bertani, Francesca R., Ciaglia, Elena, Astone, Dalila, Maulucci, Giuseppe, Cavallo, Anna, Vitale, Mario, Cimini, Vincenzo, Pastore, Lucio, Means, Anthony R., Rossi, Guido, Racioppi, Luigi
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2008
Teme:
Immunobiology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200860/
https://ncbi.nlm.nih.gov/pubmed/17909078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091173
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