Calmodulin-dependent kinase IV links Toll-like receptor 4 signaling with survival pathway of activated dendritic cells

Microbial products, including lipopolysaccharide (LPS), an agonist of Toll-like receptor 4 (TLR4), regulate the lifespan of dendritic cells (DCs) by largely undefined mechanisms. Here, we identify a role for calcium-calmodulin–dependent kinase IV (CaMKIV) in this survival program. The pharmacologic...

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Detalhes bibliográficos
Main Authors: Illario, Maddalena, Giardino-Torchia, Maria L., Sankar, Uma, Ribar, Thomas J., Galgani, Mario, Vitiello, Laura, Masci, Anna Maria, Bertani, Francesca R., Ciaglia, Elena, Astone, Dalila, Maulucci, Giuseppe, Cavallo, Anna, Vitale, Mario, Cimini, Vincenzo, Pastore, Lucio, Means, Anthony R., Rossi, Guido, Racioppi, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200860/
https://ncbi.nlm.nih.gov/pubmed/17909078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-091173
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