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Complexes between photoactivated rhodopsin and transducin: progress and questions
Activation of GPCRs (G-protein-coupled receptors) leads to conformational changes that ultimately initiate signal transduction. Activated GPCRs transiently combine with and activate heterotrimeric G-proteins resulting in GTP replacement of GDP on the G-protein α subunit. Both the detailed structural...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875673/ https://ncbi.nlm.nih.gov/pubmed/20423327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100270 |
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