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Complexes between photoactivated rhodopsin and transducin: progress and questions

Activation of GPCRs (G-protein-coupled receptors) leads to conformational changes that ultimately initiate signal transduction. Activated GPCRs transiently combine with and activate heterotrimeric G-proteins resulting in GTP replacement of GDP on the G-protein α subunit. Both the detailed structural...

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Autors principals: JASTRZEBSKA, Beata, TSYBOVSKY, Yaroslav, PALCZEWSKI, Krzysztof
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875673/
https://ncbi.nlm.nih.gov/pubmed/20423327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20100270
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