FGF20 and Parkinson's disease: No evidence of association or pathogenicity via α-synuclein expression

Genetic variation in fibroblast growth factor 20 (FGF20) has been associated with risk of Parkinson's disease (PD). Functional evidence suggested the T allele of one SNP, rs12720208 C/T, altered PD risk by increasing FGF20 and α-synuclein protein levels. Herein we report our association study o...

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Main Authors: Wider, Christian, Dachsel, Justus C., Soto, Alexandra I., Heckman, Michael G., Diehl, Nancy N., Yue, Mei, Lincoln, Sarah, Aasly, Jan O., Haugarvoll, Kristoffer, Trojanowski, John Q., Papapetropoulos, Spiridon, Mash, Deborah, Rajput, Alex, Rajput, Ali H., Gibson, J. Mark, Lynch, Timothy, Dickson, Dennis W., Uitti, Ryan J., Wszolek, Zbigniew K., Farrer, Matthew J., Ross, Owen A.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875476/
https://ncbi.nlm.nih.gov/pubmed/19133659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.22442
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