Inhibition of ABCB1 (MDR1) Expression by an siRNA Nanoparticulate Delivery System to Overcome Drug Resistance in Osteosarcoma

BACKGROUND: The use of neo-adjuvant chemotherapy in treating osteosarcoma has improved patients' average 5 year survival rate from 20% to 70% in the past 30 years. However, for patients who progress after chemotherapy, its effectiveness diminishes due to the emergence of multi-drug resistance (...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Susa, Michiro, Iyer, Arun K., Ryu, Keinosuke, Choy, Edwin, Hornicek, Francis J., Mankin, Henry, Milane, Lara, Amiji, Mansoor M., Duan, Zhenfeng
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875382/
https://ncbi.nlm.nih.gov/pubmed/20520719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010764
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars