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A Pilot Study to Evaluate the Safety and Efficacy of the Long-acting IL-1 Inhibitor, Rilonacept (IL-1 Trap) in Patients with Familial Cold Autoinflammatory Syndrome (FCAS)

OBJECTIVE: Familial cold autoinflammatory syndrome (FCAS) is caused by mutations in CIAS1 leading to excessive secretion of IL-1β, which is associated with cold induced fevers, joint pain and systemic inflammation. This pilot study was conducted to assess the safety and efficacy of the long acting I...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Goldbach-Mansky, Raphaela, Shroff, Sharukh, Wilson, Mildred, Snyder, Christopher, Plehn, Sara, Barham, Beverly, Pham, Tuyet Hang, Kastner, Daniel L., Pucino, Frank, Wesley, Robert A., Papadopoulos, Joanne, Weinstein, Steven, Mellis, Scott
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2008
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875198/
https://ncbi.nlm.nih.gov/pubmed/18668591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23620
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