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Arsenite suppresses Notch1 signaling in human keratinocytes
Arsenic is a well known human skin carcinogen whose mechanism of action remains to be elucidated. In this work using cultured human epidermal cells, arsenite suppressed accumulation of the transcriptionally active intracellular domain of Notch1. The cells responded to an active peptide from the Notc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875141/ https://ncbi.nlm.nih.gov/pubmed/18633435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.207 |
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