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Preventing Ca(2+)-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies
Overactivation of the NMDA-subtype of glutamate receptor is known to trigger excessive calcium influx, contributing to neurodegenerative conditions. Such dysregulation of calcium signaling results in generation of excessive free radicals, including reactive oxygen and nitrogen species (ROS/RNS), inc...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875138/ https://ncbi.nlm.nih.gov/pubmed/20060165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.12.009 |
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