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Preventing Ca(2+)-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies
Overactivation of the NMDA-subtype of glutamate receptor is known to trigger excessive calcium influx, contributing to neurodegenerative conditions. Such dysregulation of calcium signaling results in generation of excessive free radicals, including reactive oxygen and nitrogen species (ROS/RNS), inc...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875138/ https://ncbi.nlm.nih.gov/pubmed/20060165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.12.009 |
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