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Preventing Ca(2+)-mediated nitrosative stress in neurodegenerative diseases: Possible pharmacological strategies

Overactivation of the NMDA-subtype of glutamate receptor is known to trigger excessive calcium influx, contributing to neurodegenerative conditions. Such dysregulation of calcium signaling results in generation of excessive free radicals, including reactive oxygen and nitrogen species (ROS/RNS), inc...

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Detalhes bibliográficos
Main Authors: Nakamura, Tomohiro, Lipton, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875138/
https://ncbi.nlm.nih.gov/pubmed/20060165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2009.12.009
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