Akt1 and Akt2 promote peripheral B-cell maturation and survival

Although the 3 isoforms of Akt regulate cell growth, proliferation, and survival in a wide variety of cell types, their role in B-cell development is unknown. We assessed B-cell maturation in the bone marrow (BM) and periphery in chimeras established with fetal liver progenitors lacking Akt1 and/or...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Calamito, Marco, Juntilla, Marisa M., Thomas, Matthew, Northrup, Daniel L., Rathmell, Jeffrey, Birnbaum, Morris J., Koretzky, Gary, Allman, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2010
Gaiak:
Immunobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875094/
https://ncbi.nlm.nih.gov/pubmed/20042722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-241638
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