Llwytho...

AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening

In Escherichia coli, the TolC–AcrAB complex forms a major antibiotic efflux system with broad substrate specificity. During the complex assembly, the periplasmic helices and bottom turns of TolC are thought to interact with a hairpin helix of AcrA and hairpin loops of AcrB respectively. In the prese...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Weeks, Jon W., Celaya-Kolb, Teresa, Pecora, Sara, Misra, Rajeev
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875072/
https://ncbi.nlm.nih.gov/pubmed/20132445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07068.x
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