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Huntington's disease: progress toward effective disease-modifying treatments and a cure

Huntington's disease (HD) is caused by a dominant mutation in HTT, the HD gene. This discovery opens possibilities for treatment based on silencing of the disease-causing allele or with compounds that reduce the production of disease-causing mRNA and/or protein. Although additional developments...

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Detalhes bibliográficos
Main Authors: Johnson, Carl D., Davidson, Beverly L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875055/
https://ncbi.nlm.nih.gov/pubmed/20421366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq148
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