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Huntington's disease: progress toward effective disease-modifying treatments and a cure
Huntington's disease (HD) is caused by a dominant mutation in HTT, the HD gene. This discovery opens possibilities for treatment based on silencing of the disease-causing allele or with compounds that reduce the production of disease-causing mRNA and/or protein. Although additional developments...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875055/ https://ncbi.nlm.nih.gov/pubmed/20421366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq148 |
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