Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine mda-7/IL-24

mda-7/IL-24 is a unique member of the IL-10 gene family, which displays a broad range of antitumor properties including induction of cancer-specific apoptosis. Adenoviral mediated delivery by Ad.mda-7 invokes an endoplasmic reticulum stress response that is associated with ceramide production and au...

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Autori principali: Bhutia, Sujit K., Dash, Rupesh, Das, Swadesh K., Azab, Belal, Su, Zhao-zhong, Lee, Seok-Geun, Grant, Steven, Yacoub, Adly, Dent, Paul, Curiel, David T., Sarkar, Devanand, Fisher, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874885/
https://ncbi.nlm.nih.gov/pubmed/20406981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3647
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