Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis

Multiple angiogenesis inhibitors have been therapeutically validated in preclinical cancer models, and several in clinical trials. Here we report that angiogenesis inhibitors targeting the VEGF pathway demonstrate antitumor effects in mouse models of pancreatic neuroendocrine carcinoma and glioblast...

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Détails bibliographiques
Auteurs principaux: Pàez-Ribes, Marta, Allen, Elizabeth, Hudock, James, Takeda, Takaaki, Okuyama, Hiroaki, Viñals, Francesc, Inoue, Masahiro, Bergers, Gabriele, Hanahan, Douglas, Casanovas, Oriol
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874829/
https://ncbi.nlm.nih.gov/pubmed/19249680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2009.01.027
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